Build biology with the right tools
Liftoff.bio is a curated directory of the software, models and databases powering modern TechBio — from AlphaFold-class structure prediction to single-cell analysis, lab automation and beyond.
Explore by category
Twelve corners of computational biology
Every tool is tagged and searchable. Start from a category or search the whole catalog.
AI Models
Structure prediction, protein design and biological foundation models — from AlphaFold-class co-folding to DNA and protein language models.
Genomics & Sequencing
Alignment, variant calling, quantification and sequence search for short- and long-read data.
Single-Cell & Spatial
Analysis frameworks, probabilistic models and atlases for single-cell and spatial omics.
Bioimage Analysis
Segmentation, visualization and quantitative analysis of microscopy images at any scale.
Workflow Orchestration
Reproducible, portable pipelines that scale from a laptop to HPC clusters and the cloud.
Libraries & SDKs
Battle-tested programming libraries for parsing, manipulating and analysing biological data.
Structural Biology
Visualize, search, compare and simulate macromolecular structures — experimental or predicted.
Cheminformatics & Drug Discovery
Small-molecule toolkits, docking, binding affinity and molecular simulation for drug discovery.
LIMS & ELN
Laboratory information management and electronic lab notebooks to track samples, protocols and results.
Lab Automation
Program liquid handlers and robots in code, or run experiments remotely in cloud labs.
Public Databases
Open knowledgebases for sequences, structures, expression and chemistry — the training data of modern biology.
Molecular Biology & Editing
Design primers, plasmids and CRISPR guides, and source reagents for the bench.
Hand-picked
Featured tools
A rotating selection of the tools we reach for most often.
Public Databases
RCSB Protein Data Bank
The global archive of 3D biomolecular structures
Lab Automation
Opentrons
Affordable, open lab robots you program in Python
Cheminformatics & Drug Discovery
RDKit
The open-source cheminformatics toolkit
From the blog
Guides and explainers on the fast-moving world of TechBio — foundation models, reproducible pipelines, single-cell analysis and programming the wet lab.
Programming the wet lab
Liquid handlers you script in Python, hardware-agnostic robot frameworks and modern lab notebooks are closing the loop between code and the bench.
A starter stack for single-cell analysis
From raw counts to annotated clusters: the Python and R tools that form the backbone of single-cell genomics.
Reproducible pipelines: Nextflow vs. Snakemake in 2026
The two dominant workflow managers have both shipped major releases. How to choose, and what changed.
Not sure which tool to use?
Ask the Liftoff.bio assistant. It knows the catalog and can recommend tools for your task, compare options and point you to docs.